Celiac Plexus Neurolysis

Advanced pain management for pancreatic cancer and chronic pancreatitis

About Celiac Plexus Neurolysis

Celiac plexus neurolysis is a specialized procedure that targets the celiac plexus, a network of nerves surrounding the major blood vessels in the abdomen. These nerves transmit pain signals from the pancreas, liver, gallbladder, stomach, and other abdominal organs to the brain. By precisely injecting alcohol or phenol into this nerve cluster, the procedure destroys or permanently blocks these pain pathways, providing significant relief for patients suffering from severe abdominal pain, particularly from pancreatic cancer or chronic pancreatitis.

Unlike temporary nerve blocks that use local anesthetics, neurolysis offers longer-lasting pain relief by actually disrupting the nerve fibers. This makes it an important option for patients with advanced pancreatic cancer or those with intractable pain from chronic pancreatitis who haven't responded to other treatments.

Long-lasting Relief

Provides extended pain control for pancreatic and upper abdominal pain

Minimally Invasive

Performed as an outpatient procedure in most cases

Improved Quality of Life

Reduces reliance on opioid medications and their side effects

Who Can Benefit

Celiac plexus neurolysis is particularly beneficial for patients with:

  • Pancreatic cancer with severe abdominal pain not adequately controlled by medications
  • Chronic pancreatitis with persistent pain despite medical management
  • Patients experiencing significant side effects from high-dose opioid pain medications
  • Individuals with upper abdominal cancer who need improved pain control for better quality of life
  • Patients who have responded well to a temporary celiac plexus block with local anesthetic

Dr. Hemani will conduct a thorough evaluation to determine if celiac plexus neurolysis is appropriate for your specific condition and pain management needs. This often includes reviewing imaging studies, previous treatments, and your overall health status.

Approaches and Techniques

Dr. Hemani may use different approaches to perform celiac plexus neurolysis, depending on your specific condition, anatomy, and other factors:

Posterior Approach

The traditional and most common technique, where needles are inserted through the back, passing alongside the spine to reach the celiac plexus. This approach can be performed with the patient under moderate sedation and is often used in outpatient settings.

Anterior Approach

In some cases, particularly when tumors or anatomical variations make the posterior approach difficult, needles may be inserted through the abdomen under CT guidance. This approach may be preferred for patients who cannot lie prone (face down).

Endoscopic Ultrasound-Guided Approach

A newer technique where the neurolytic agent is delivered through an endoscope (a flexible tube with a camera) passed through the mouth and stomach. This approach allows for very precise targeting under direct ultrasound visualization and is typically performed under general anesthesia.

Choosing the Right Approach

Dr. Hemani will recommend the most appropriate approach based on your specific condition, tumor location (if applicable), overall health status, and previous surgical history. Each technique has its own advantages, and the choice is individualized to provide the safest and most effective outcome for each patient.

Frequently Asked Questions

Schedule a Consultation

If you're suffering from chronic abdominal pain, Dr. Hemani can help determine if celiac plexus neurolysis is right for you. Contact us today to schedule your consultation.

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Medical Disclaimer: The information provided on this page is for educational purposes only and is not intended as medical advice. Please consult with Dr. Hemani or another qualified healthcare provider for personalized medical advice.